Endocrine Abstracts

In birds similar to mammalian species, the reproductive performance in females deteriorates with age. In the present study, relationships between the growth of preovulatory follicles (PF), reproductive aging and sex steroids were investigated using young hens with long clutch (YLC), old hens with long clutch (OLC) and old hens with short clutch (OSC). 1) hens were killed 1.5 and 14.5 h after assumed ovulation. 2) YLC hens were killed 3.5 h after treatments with LH and/or amino...

The aim of our study was to examine the influence of green tea molecules on basic ovarian functions. For this purpose we have examine the effect of green tea extract, fraction of antioxidants (GTAO) and green tea fraction of polyphenols (GTPP) (at the doses 0, 1, 10, and 100 μg/ml) on proliferation, apoptosis, and steroidogenesis by cultured porcine ovarian granulosa cells. Markers of proliferation (PCNA) and apoptosis (bax) were detected by immunocytochemistry. Secretion...

The recent original data concerning interrelationships between metabolic hormones (ghrelin, leptin, obestatin) and feeding, action of metabolic hormones on basic ovarian functions (proliferation, apoptosis, secretory activity, response to gonadotropins, oocyte maturation) and intracellular mechanisms of its action in different species (rabbit, pig, human, chicken) are reviewed. It was shown, that metabolic hormones ghrelin, leptin and obestatin can control proliferation, apopt...

Occurence of mycotoxins in various food and feed commodities is a worldwide problem. T-2 toxin is one of the most toxic trichothecene mycotoxin, produced mainly by Fusarium species. Poultry belongs to very sensitive species which are very often explored to toxic effects of mycotoxins. The aim of our in vitro studies was to examine secretion activity of ovarian granulossa cells to produce progesterone P4 after T-2 toxin and its combinations with res...